Palbociclib Impurity 87 HCl CAS 2174002-29-8(free base)
| CAS No. | 2174002-29-8(free base) |
| Molecular Formula | C24H29N7O3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Palbociclib Impurity 87 HCl is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Palbociclib Impurity 87 HCl (CAS 2174002-29-8(free base)) is a certified pharmaceutical impurity reference standard with the molecular formula C24H29N7O3HCl and a molecular weight of 500.00 g/mol.
Based on its molecular formula C24H29N7O3HCl, Palbociclib Impurity 87 HCl contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 500.00 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Palbociclib Impurity 87 HCl meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H29N7O3 HCl |
| Molecular Weight | 500.00 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 7 |
Related Palbociclib Standards
- Palbociclib Impurity 96 (CAS 1013916-37-4)
- Palbociclib Impurity 25 (CAS 1016636-76-2)
- Palbociclib Impurity 6 (CAS 1023594-49-1)
- Palbociclib Impurity 26 (CAS 1023594-50-4)
- Palbociclib Impurity 2 (CAS 1072-97-5)
- Palbociclib Impurity 32 (CAS 1082876-26-3)
- Palbociclib Impurity 204 (CAS 119285-06-2（free base）)
- Palbociclib Impurity 208 (CAS 120613-50-5)
Recommended Standards
- Baloxavir Impurity 150 (CAS CATO-C4X-2108150)
- Venetoclax Impurity 97 (CAS CATO-C4X-249597)
- Alogliptin Impurity 61 (CAS 162955-48-8)
- N-(3-aminophenyl)-N’-isopropylurea (CAS 1042554-38-0)
- Methyl 3-Phenylisonicotinate (CAS 850162-87-7)
- 2-(3-(4-Methylbenzyl)-2,4,5-trioxoimidazolidin-1-yl)acetamide (CAS 303986-63-2)
- (2S,3S)-3-((tert-butoxycarbonyl)amino)-2-hydroxy-3-(4-methoxyphenyl)propanoic acid (CAS 959576-39-7)
- tert-Butyl 3-benzyl-3,6-diazabicyclo[3.2.0]heptane-6-carboxylate (CAS 122828-36-8)
- N1-(2-(dimethylamino)phenyl)-N2,N2-dimethylbenzene-1,2-diamine (CAS 1072901-09-7)
- (Leu31,Pro3?)-Neuropeptide Y (human, rat) trifluoroacetate salt (CAS 132699-73-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com